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Enabling Nanoscale Advances
Park Systems has always strived to push the limits of innovation in scan

Park Systems, formally PSIA, is an innovative leader in atomic force microscopy. We are committed to providing accurate yet easy to use AFMs. With features like True Non-Contact™ mode and automated software, we continue to achieve our goals of improving our products. Headquartered in South Korea, Park Systems also hosts offices in the United States, Germany, China, Mexico, Singapore, India and Japan.

04/06/2026

𝗛𝗼𝘄 𝗰𝗮𝗻 𝗵𝗶𝗱𝗱𝗲𝗻 𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝘆 𝗶𝗻 𝘀𝗲𝗺𝗶𝗰𝗼𝗻𝗱𝘂𝗰𝘁𝗼𝗿 𝘁𝗵𝗶𝗻 𝗳𝗶𝗹𝗺𝘀 𝗯𝗲 𝗿𝗲𝘃𝗲𝗮𝗹𝗲𝗱 𝗮𝘁 𝘁𝗵𝗲 𝗻𝗮𝗻𝗼𝘀𝗰𝗮𝗹𝗲?
Led by 𝗗𝗿. 𝗜𝗻 𝗛𝘄𝗮 𝗖𝗵𝗼, the Pusan National University research team used 𝗣𝗮𝗿𝗸 𝗙𝗫𝟮𝟬𝟬 𝗜𝗥 to go beyond topography and map local chemical composition in multilayer semiconductor films.

𝗖𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲: identify trace organic additives and layer-specific chemistry in thin film structures.
𝗔𝗽𝗽𝗿𝗼𝗮𝗰𝗵: Nano-IR molecular vibration detection with AFM-based spatial precision.
𝗥𝗲𝘀𝘂𝗹𝘁: clear cross-sectional layer distinction, functional group data from multiple samples, and published research based on FX200 IR findings.

A strong example of how nanoscale IR can turn complex interfaces into interpretable chemical data.

📜𝗥𝗲𝗮𝗱 𝘁𝗵𝗲 𝗰𝗮𝘀𝗲 𝘀𝘁𝘂𝗱𝘆 𝗮𝗻𝗱 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿 𝘁𝗵𝗲 𝗡𝗮𝗻𝗼-𝗜𝗥 𝗰𝗮𝗽𝗮𝗯𝗶𝗹𝗶𝘁𝗶𝗲𝘀 𝗼𝗳 𝗣𝗮𝗿𝗸 𝗙𝗫𝟮𝟬𝟬 𝗜𝗥: https://okt.to/C28BYX

03/06/2026

𝗛𝗼𝘄 𝗺𝘂𝗰𝗵 𝘁𝗶𝗺𝗲 𝗰𝗼𝘂𝗹𝗱 𝘆𝗼𝘂 𝘀𝗮𝘃𝗲 𝗶𝗳 𝗻𝗮𝗻𝗼𝘀𝗰𝗮𝗹𝗲 𝗜𝗥 𝘀𝗲𝘁𝘂𝗽 𝗮𝗹𝗶𝗴𝗻𝗲𝗱 𝗶𝘁𝘀𝗲𝗹𝗳?
𝗣𝗮𝗿𝗸 𝗡𝗮𝗻𝗼-𝗜𝗥 𝗦𝗽𝗲𝗰𝘁𝗿𝗼𝗺𝗲𝘁𝗲𝗿𝘀 streamline AFM-integrated IR spectroscopy with automation built for repeatable, high-resolution chemical analysis.

𝗞𝗲𝘆 𝗮𝘂𝘁𝗼𝗺𝗮𝘁𝗶𝗼𝗻 𝗵𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀:
🔸 SmartScan™ automatic IR beam alignment using real-time nano-IR signal feedback
🔸 One-click spectrum visualization and chemical overlay in SmartAnalysis™
🔸 Automated probe exchange and AFM laser beam alignment on the FX platform
🔸 Non-contact PiFM detection to reduce sample damage and tip contamination
🔸 Stable nano-IR imaging with optimized detection frequency tracking

Built for semiconductor FA, polymers, thin films, 2D materials, and advanced materials R&D.

💡Explore 𝗣𝗮𝗿𝗸 𝗡𝗮𝗻𝗼-𝗜𝗥 𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻𝘀, from the 𝗙𝗫𝟮𝟬𝟬 𝗜𝗥 and 𝗙𝗫𝟯𝟬𝟬 𝗜𝗥 for large-sample analysis to the newly launched 𝗙𝗫𝟰𝟬 𝗜𝗥 for small-sample research: https://okt.to/XbAufE

03/06/2026

Our French Team will be at the 𝗙𝗼𝗿𝘂𝗺 𝗱𝗲𝘀 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝗶𝗲𝘀 à 𝗦𝗼𝗻𝗱𝗲𝘀 𝗟𝗼𝗰𝗮𝗹𝗲𝘀 𝟮𝟬𝟮𝟲 next week in Saint-Rémy-lès-Chevreuse.

Come and meet Romain Bourrellier , Geoffrey Morelle and Matthew Lefevre at our booth to discover the 𝗡𝗫𝟭 and 𝗡𝗫𝟭𝟬 𝗔𝗙𝗠 systems, including the 𝗖𝗮𝘆𝗹𝗮𝗿 𝗠𝗙𝗚 setup for magnetic-field applications.

We will also host a small 𝗴𝗲𝘁-𝘁𝗼𝗴𝗲𝘁𝗵𝗲𝗿 𝗮𝘁 𝗼𝘂𝗿 𝗯𝗼𝗼𝘁𝗵 𝗼𝗻 𝗧𝘂𝗲𝘀𝗱𝗮𝘆, 𝟵 𝗝𝘂𝗻𝗲. Join us for an informal exchange with the Park Systems team and the local probe microscopy community.

Au plaisir de vous retrouver sur place.

💡𝗙𝗶𝗻𝗱 𝗼𝘂𝘁 𝗺𝗼𝗿𝗲: https://okt.to/SjMrT1

02/06/2026

From the first AFM experiments to true atomic resolution, 𝗣𝗿𝗼𝗳. 𝗙𝗿𝗮𝗻𝘇 𝗝. 𝗚𝗶𝗲𝘀𝘀𝗶𝗯𝗹’𝘀 𝘀𝘁𝗼𝗿𝘆 𝗶𝘀 𝗼𝗻𝗲 𝗼𝗳 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗽𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝗰𝗲.
In this interview, he reflects on working with Gerd Binnig, the pursuit of sub-angstrom resolution, and the evolution from Orpheus II to 𝗣𝗮𝗿𝗸 𝗡𝗫𝟭. What began as a research concept for experts is now becoming a practical platform for ambient atomic-resolution AFM.

Watch the interview to hear 𝗵𝗼𝘄 𝗮 𝗹𝗶𝗳𝗲𝘁𝗶𝗺𝗲 𝗼𝗳 𝗔𝗙𝗠 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗵𝗲𝗹𝗽𝗲𝗱 𝘀𝗵𝗮𝗽𝗲 𝗣𝗮𝗿𝗸 𝗡𝗫𝟭 and why seeing, understanding, and mastering the sensor still matters for the next generation of researchers.

🎥𝗪𝗮𝘁𝗰𝗵 𝘁𝗵𝗲 𝗶𝗻𝘁𝗲𝗿𝘃𝗶𝗲𝘄: https://okt.to/CgxavT

01/06/2026

[𝗗𝗛𝗠 𝗪𝗲𝗲𝗸: 𝗟𝗮𝗯𝗲𝗹-𝗙𝗿𝗲𝗲 𝗩𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆: 𝗗𝗛𝗠 𝗠𝗲𝗲𝘁𝘀 𝟰𝗗 𝗧𝗿𝗮𝗰𝗸𝗶𝗻𝗴 / 𝗕𝗼𝗻𝘂𝘀 𝗘𝗽𝗶𝘀𝗼𝗱𝗲]
This latest paper reports a new DHM 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗳𝗼𝗿 𝗾𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗲 𝗳𝗹𝗮𝗴𝗲𝗹𝗹𝗮𝗿 𝗸𝗶𝗻𝗲𝗺𝗮𝘁𝗶𝗰𝘀. The researchers show how to quantitatively capture rapid, highly non-planar flagellar motion in true 3D without labeling or mechanical z-scanning. By combining single-shot volumetric acquisition with dedicated tracking software, 𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗛𝗼𝗹𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 (𝗗𝗛𝗠) enables precise tracking of complex eukaryotic flagella with high temporal and axial resolution.

✅ Single-shot 3D capture of the full sample volume
✅ Quantitative reconstruction of complex non-planar flagellar waveforms
✅ High axial precision for dense 4D kinematic measurements
✅ Label-free tracking of fast biological dynamics

The method was validated on both mouse spermatozoa and the protist Reclinomonas americana, including reconstruction of highly non-planar beating patterns of a flagellum only ~200 nm in diameter.

This application highlights how DHM extends beyond imaging toward quantitative 4D analysis of complex biological motion, with potential applications in reproductive biology, microbial ecology, motility research, and drug screening.

📖 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝘁𝗵𝗲 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗱 𝗿𝗲𝗮𝗱 𝘁𝗵𝗲 𝗽𝗮𝗽𝗲𝗿: https://okt.to/Jz7iGp
💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗼𝘂𝗿 𝗗𝗛𝗠 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝘀 for real‑time quantitative imaging: https://okt.to/riYJWa

29/05/2026

📢𝗣𝗿𝗼𝗱𝘂𝗰𝘁 𝗟𝗮𝘂𝗻𝗰𝗵 𝗔𝗻𝗻𝗼𝘂𝗻𝗰𝗲𝗺𝗲𝗻𝘁: 𝗠𝗲𝗲𝘁 𝗣𝗮𝗿𝗸 𝗙𝗫𝟰𝟬 𝗜𝗥
The most advanced 𝗔𝗙𝗠 𝘄𝗶𝘁𝗵 𝗡𝗮𝗻𝗼-𝗜𝗥 𝗳𝗼𝗿 𝘀𝗺𝗮𝗹𝗹 𝘀𝗮𝗺𝗽𝗹𝗲𝘀 is here.
FX40 IR combines high-performance AFM with nanoscale infrared spectroscopy and imaging, enabling chemical and surface characterization on the proven FX40 platform.

𝗛𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀:
✅ Sub-5 nm spatial resolution with Photo-induced Force Microscopy (PiFM)
✅ True Non-Contact™ Nano-IR for fragile samples
✅ Automatic IR beam alignment for simplified setup
✅ Selectable Direct and Sideband detection modes
✅ Built for polymers, photoresists, semiconductor materials, 2D materials, thin films, surface contamination, defect analysis, and nanoscale chemical mapping

Ready to reveal chemistry beyond conventional AFM imaging?

💡𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗺𝗼𝗿𝗲: https://www.parksystems.com/en/products/research-afm/small-sample-afm/fx40-ir_campaign?utm_source=organic-facebook&utm_medium=social&utm_campaign=hq-FX40_IR_product_launch_260530-2026-05-29-CM005

29/05/2026

[𝗗𝗛𝗠 𝗪𝗲𝗲𝗸: 𝗟𝗮𝗯𝗲𝗹-𝗙𝗿𝗲𝗲 𝗩𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆: 𝗖𝗮𝗿𝗱𝗶𝗼𝘁𝗼𝘅𝗶𝗰𝗶𝘁𝘆 / 𝗘𝗽𝗶𝘀𝗼𝗱𝗲 𝟱]
How early can you see a drug candidate disturbing cardiomyocyte function?
Cardiotoxicity remains a major risk in therapeutic development.
Identifying adverse cardiac effects early in the pre-clinical phase is not just a safety win, it can save millions of dollars by preventing costly failures in later clinical trials.

𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗛𝗼𝗹𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 (𝗗𝗛𝗠) provides a label-free way to quantify beating cardiomyocytes by measuring dry mass movement and mechanical contraction dynamics, while fluorescence can be added when calcium correlation is needed.

For drug-development workflows, DHM can extract multiple beating-profile parameters from living cardiomyocytes without adding labels. This helps researchers follow functional effects, rhythm changes, and contraction behavior in a less perturbing way.

𝗢𝘂𝘁𝗹𝗼𝗼𝗸: earlier cardiac safety signals, richer dynamic profiles, and more confidence before candidates move forward.

💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗺𝗼𝗿𝗲: https://okt.to/Mje6AN
💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗼𝘂𝗿 𝗗𝗛𝗠 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝘀: https://okt.to/xdVOyC

Image Caption: Temporal correlation of cardiomyocyte beating recorded with DHM and fluorescence

28/05/2026

[𝗗𝗛𝗠 𝗪𝗲𝗲𝗸: 𝗟𝗮𝗯𝗲𝗹-𝗙𝗿𝗲𝗲 𝗩𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆: 𝗧𝘂𝗺𝗼𝗿 𝗖𝗲𝗹𝗹 𝗜𝗻𝘃𝗮𝘀𝗶𝗼𝗻 / 𝗘𝗽𝗶𝘀𝗼𝗱𝗲 𝟰]
Can tumor invasion be measured before cells visibly migrate?
In this paper, Zhaobin Guo et al. used 𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗛𝗼𝗹𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 (𝗗𝗛𝗠) to map nano- to submicrometer optical thickness fluctuations inside single tumor cells embedded in 3D gel environments that mimic tissue-like conditions.

These fluctuations, driven by dynamic intracellular structures including the cytoskeleton, were linked to tumor cell motility and invasiveness.
The study also showed that micromotion decreased when cells were treated with migrastatic drugs, supporting DHM as a rapid, label-free tool to assess invasive behavior and anti-invasive strategies.

𝗢𝘂𝘁𝗹𝗼𝗼𝗸: DHM could help cancer researchers detect invasive potential earlier, at single-cell level, with less perturbation.

📜 𝗥𝗲𝗮𝗱 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝗽𝗮𝗽𝗲𝗿: https://okt.to/SgFzq4
💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗼𝘂𝗿 𝗗𝗛𝗠 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝘀: https://okt.to/SJM2LO

Image Caption: DHM maps optical thickness fluctuations to generate a Micromotion Index, revealing EGF-induced invasive behavior in 3D cell migration.

26/05/2026

[𝗗𝗛𝗠 𝗪𝗲𝗲𝗸: 𝗟𝗮𝗯𝗲𝗹-𝗙𝗿𝗲𝗲 𝗩𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆: 𝗖𝗮𝗻𝗰𝗲𝗿 𝗣𝗵𝗲𝗻𝗼𝘁𝘆𝗽𝗶𝗻𝗴 / 𝗘𝗽𝗶𝘀𝗼𝗱𝗲 𝟯]
Can cancer cell aggressiveness be detected from intrinsic cell dynamics, without markers?
𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗛𝗼𝗹𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 (𝗗𝗛𝗠) measures quantitative phase information from living cells, giving access to optical thickness, morphology, dry mass, and dynamic intracellular fluctuations.
For cancer research, this opens a different readout: label-free phenotyping of metabolic activity, micromotion, and morphology associated with malignancy and invasiveness.

Instead of relying only on endpoint labels, DHM helps researchers observe how living cancer cells behave over time, including subtle changes in intracellular activity and cell response to treatment-relevant conditions.

𝗢𝘂𝘁𝗹𝗼𝗼𝗸: DHM may help connect cell mechanics, metabolism, and therapy response earlier in the research pipeline.

💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗺𝗼𝗿𝗲: https://okt.to/1vKNFm
💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗼𝘂𝗿 𝗗𝗛𝗠 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝘀: https://okt.to/wvNOEy

Image Caption: “Hotspots" of metabolic regions in cancer cells observed via DHM

26/05/2026

[𝗗𝗛𝗠 𝗪𝗲𝗲𝗸: 𝗟𝗮𝗯𝗲𝗹-𝗙𝗿𝗲𝗲 𝗩𝗶𝗮𝗯𝗶𝗹𝗶𝘁𝘆: 𝗖𝘆𝘁𝗼𝘁𝗼𝘅𝗶𝗰𝗶𝘁𝘆 𝗦𝗰𝗿𝗲𝗲𝗻𝗶𝗻𝗴 / 𝗘𝗽𝗶𝘀𝗼𝗱𝗲 𝟮]
What if cytotoxicity screening could reveal cell death dynamics without staining the cells?
𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗛𝗼𝗹𝗼𝗴𝗿𝗮𝗽𝗵𝗶𝗰 𝗠𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 (𝗗𝗛𝗠) turns transparent living cells into quantitative data. In cytotoxicity assays, it captures viability confluence, morphology, and phenotype changes label-free, supporting endpoint and time-lapse readouts in 96- and 384-well formats.

For drug discovery teams, this means faster insight into cytotoxic agents, cytoprotective compounds, and dose-response behavior. DHM can help quantify viability-related changes such as cell area, percentage of cell death, dry mass, and morphological response while keeping cells available for downstream analysis.

𝗢𝘂𝘁𝗹𝗼𝗼𝗸: more information per well, fewer perturbations, stronger hit prioritization.

💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗺𝗼𝗿𝗲: https://okt.to/cmIqlW
💡 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝗼𝘂𝗿 𝗗𝗛𝗠 𝗽𝗿𝗼𝗱𝘂𝗰𝘁𝘀: https://okt.to/diJyxW

Image Caption: HeLa control well vs. Doxorubicin-treated HeLa cells

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