Genomatix

23/02/2018

EURenOmics - A European success story

The EU has published an article about the success of the EURenOmics project. Genomatix is proud to have contributed to this success with software, databases and the knowledge of our consultants. Read more at:

An EU-funded project has provided new hope for the 2 million people in Europe who suffer from rare kidney diseases thanks to groundbreaking research that has led to diagnostic tests and a new type of treatment.

17/10/2017

This study made use of our MatInspector software to identify potential estrogen response elements in the MLK3 gene promoter.

Mixed Lineage Kinase 3 (MLK3), also called as MAP3K11 is a tightly regulated MAP3K member but its cellular function is still not fully understood. Earlier we reported post-translational regulation of MLK3 by estrogen (E2) that inhibited the kinase activity ...

04/10/2017

Here's a new publication with data and support from the SYNERGY and the RADIANT EU projects looking at ChIP-Seq time course data to predict enhancer-promoter interactions.

We have developed a machine learning approach to predict stimulation-dependent enhancer-promoter interactions using evidence from changes in genomic protein occupancy over time. The occupancy of estrogen receptor alpha (ERα), RNA polymerase (Pol II) and histone marks H2AZ and H3K4me3 were measured o...

12/07/2017

This collaborative publication was among the top 10% cited PLOS ONE papers in June: https://doi.org/10.1371/journal.pone.0024351. The Genomatix Pathway System was used for the analysis.

Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction of pluripotency, we have analyzed transcriptional profiles at 24, 48 and 72 hours post-transduction of…

04/04/2017

The EURenOmics consortium has produced some video interviews with selected partners. Take a look if you're interested in rare disease in kidney research and want to find out more about the consortium.

https://www.youtube.com/playlist?list=PLgNh-zdzGt5mQ3cVIdIszCQbWJJtURr6y

28/02/2017

Today is rare disease day! Visit http://www.rarediseaseday.org to learn more and spread the word.

The main objective of Rare Disease Day 2017 is to raise awareness with policy makers and the public of rare diseases and of their impact on the lives of patients, and to reinforce their importance as a public health priority.

16/02/2017

We're happy that our tools were helpful for the data analysis in this pre-clinical colon cancer study from the OncoTrack consortium. http://www.nature.com/articles/ncomms14262

The heterogeneity of colorectal cancer has important clinical and therapeutic implications. Here the authors analysed the responses of a large biobank of organoids and xenografts derived from colorectal patients to a panel of clinically relevant therapeutic agents to identify genes signatures associ...

25/01/2017

Join us later today for our "Introduction to the Genomatix Pathway System" webinar at 4pm CET. Use the link below to register your seat.

The webinar will give you an introduction to the Genomatix Pathway System, including examples how to generate networks from gene lists, access and review the underlying literature and transcription factor data, edit networks using literature information, extend networks with transcription factors and work with transcription factor filters and summaries.

https://attendee.gotowebinar.com/register/691350201117105155

Do you work with large scale gene expression / regulation data, such as RNA-Seq or microarrays? Then you'll want to reveal the hidden biology and regulatory networks in your gene sets, using pathway analysis. The Genomatix Pathway System integrates multiple lines of evidence to generate information-...

09/12/2016

Only 3 more weeks before Christmas! This week's Genomatix Christmas surprise is all about pathways and literature - create networks, display pathways and use the information you get from literature and from your own work to do so. Export your individual networks for publications and talks. Have a look at Genomatix Literature and Pathways software and see for yourself. Write to [email protected] for a trial or visit our shop for the latest Genomatix Christmas specials.

Don't miss any Genomatix Christmas surprises and visit us again on Friday next week.

08/12/2016

A recording of our December webinar "Comparative promoter analysis with Genomatix" is now available on youtube. You can watch it here: https://youtu.be/DEQAyyFInnw

In silico promoter analysis can give you many transcription factor binding site (TFBS) matches in a promoter. The question is: Which of them are functional? ...

02/12/2016

As promised here are the next Genomatix parcels to sweeten the time before Christmas. This week we focus on promoter analysis. To supplement our free webinar about promoter analysis on Dec. 7, at 4pm CET we offer two exceptional 3 months licenses: Genomatix Gene Regulation software for 895,- EUR or the Gene Regulation plus our Genes & Genomes software for 1495,-. Runtime is 3 months.
Send us an email at [email protected] if you are interested! Or check out the Genomatix specials on http://shop.genomatix.de/index.php?page=categorie&cat=50

25/11/2016

Black Friday Special.

For Black Friday we revived the MatInspector only license. We hope to make many people happy when finding this one among our special offers during the weeks before Christmas.

The license runs for 1 month and comes at affordable 75,00 EUR. Send us an email at [email protected] if you are interested!

Check out our specials and visit the Genomatix online shop for more information:
http://shop.genomatix.de