CrystoGen

03/03/2026

CrystalGrower is about to begin its next exciting chapter.

With the incredible growth we’ve experienced and the valuable feedback from our community, we’re preparing to take a bold new step forward.

As we evolve, our commitment remains the same. We will continue to align with our core values of transparency, inclusivity, innovation, and education.

This is more than change. It’s growth with purpose!

Stay tuned.

04/02/2026

03/02/2026

New paper featuring CrystalGrower!

In a new collaboration with UCB, it was demonstrated that the CrystalGrower platform provides early, science-based orientation for crystallisation-driven particle engineering to accelerate Direct Compression (DC) development.

CrystalGrower was used to identify viable particle engineering levers, enabling targeted small-scale experiments and efficient mapping of particle–powder relationships.

Combined with formulation prediction and tablet press validation, the workflow enabled high drug load DC for the challenging NCE Minzasolmin.

Read the paper to explore how CrystalGrower helps break CMC silos and reduce trial-and-error in solid dosage development.

https://doi.org/10.1016/j.ijpharm.2026.126618

14/01/2026

A new year deserves a new GUI. Meet CrystalGrower 2026.

We’re starting the new year with the release of CrystalGrower 2026, now live online and packed with improvements. The update introduces a modernised GUI, including a sleek dark mode, alongside bug fixes and powerful new features designed to make crystal growth modelling smoother and more intuitive.

What’s new?
• Simplified energy prediction with easy solvent screening
• New capabilities for modelling growth on surfaces
• Streamlined workflows for multiple net files
• A major update to CGAspects for visualisation and data processing
• Reorganised downloads by operating system for easier setup

With the previous version retiring at the end of 2025, now is the perfect moment to upgrade and step into the new year with the latest tools.

Visit our website to access the academic version or email us at [email protected].

Thank you to our community for growing with us. Stay tuned for a big announcement later this year!

16/12/2025

What a great few days at the MRS Fall Conference!

From great conversations at our stand to exploring Boston’s museums and architecture, it was a fantastic few days in the city. We even managed to catch the Boston Celtics take the win against the New York Knicks 🏀

Thanks to everyone who stopped by to chat. If you didn’t get a chance to speak with us, feel free to get in touch or follow along for updates. See you at the next conference!

28/11/2025

Come meet us at Booth 806 to explore how CrystalGrower can support your crystal engineering, materials science, and morphology prediction research.

Exhibit Show Times:

Tuesday, December 2 | 11:00 am – 6:00 pm

Wednesday, December 3 | 11:00 am – 5:00 pm

Thursday, December 4 | 10:00 am – 2:00 pm

We’re excited to connect with researchers, industry partners, and anyone curious about the science behind crystal growth. See you in Boston!

07/11/2025

Crystals growing on surfaces

Did you know CrystalGrower can simulate interfacial growth to visualise how varying interfacial energy affects crystal morphology?

Our latest simulation shows how these surface interactions influence the overall growth process, providing a valuable insight and a means to control crystallisation at interfaces.

We’ll be showcasing this and more at the MRS Fall Meeting. Come and see how CrystalGrower can bring your crystallisation research to life!

17/10/2025

We’re proud to share that our Chief Scientific Officer, Dr Adam Hill, has co-authored a new paper in the Journal of the American Chemical Society! 🎉

The study benchmarks computational models to understand how flexible molecules balance internal strain and intermolecular forces when forming crystal structures. The team identified a best-in-class method (PBE-MBD/B2PLYPD) and uncovered a fascinating “40% limit” that showed how much intramolecular energy can be offset during crystallisation.

This work provides a new framework for predicting crystallisability and advancing crystal structure prediction.

Flexible molecules change their conformations to optimize intermolecular interactions in the solid-state ─a process that comes at an intramolecular energy cost. The interplay between these opposing forces leads to beautifully balanced and elegant crystal structures. Yet, the relationship between i...

30/09/2025

We’re excited to share that CrystalGrower will be exhibiting at the 2025 MRS Fall Meeting & Exhibit!

📍 Booth 806
📅 November 30 – December 5, 2025
📌 Hynes Convention Centre & Sheraton Boston Hotel, Boston, Massachusetts

We look forward to connecting with researchers, industry professionals, and collaborators at . Come by our booth to learn more about CrystalGrower and how we’re advancing crystal growth research.

12/09/2025

High-Speed AFM in Action!

Check out paracetamol crystals captured at 2 frames per second using high-speed AFM, revealing stunning high-index terrace facetting in real time.

This level of detail allows researchers to observe crystal growth dynamics like never before, helping to understand morphological evolution and optimise processes in pharmaceuticals.

29/08/2025

Exciting news from the CrystalGrower team!

We’re thrilled to announce that Alvin is now joining us full-time as our dedicated software developer.

Many of you will already know Alvin from his PhD research and his contributions to CrystalGrower over the past few years. Now, with him on board full-time, we’re ramping up our development efforts to deliver even more for our users.

This means faster updates, new features, and more tailored development to meet the evolving needs of both industry and academic users. Whether it's improved performance, new crystal systems, or more intuitive user experiences, we’re working on it!

We’re excited about what’s ahead and look forward to sharing more soon. Welcome officially to the team, Alvin!

22/07/2025

This image shows the Hirshfeld surface of an agrochemical molecule crystallised along its principal bond chain grown in toluene.

Our researchers can simulate and visualise how solvents and molecular packing influence crystal shape and surface interactions, insights that are vital for formulation, stability, and bioavailability in the agrochemical industry.

Curious how solvent choice changes the final morphology?
Interested in predictive modelling to streamline development?
Contact us today at [email protected]